AQA GCSE Hormones and human reproduction(Biology)

Hormones and human reproduction

As a result of puberty hormones trigger secondary sexual characteristics.

Secondary sexual characteristicMale, female or both
Breast developmentFemale
Facial hair growthMale
Body hair growthBoth
Voice breaking Male
Menstruation startsFemale
Sperm production startsMale

Main reproductive hormones

The two main reproductive hormones are:

1.Oestrogen in females.

2.Testosterone in males.

OestrogenTestosterone
Site of productionOvariesTestes
EffectsInhibits the release of FSH, stimulates the release of LH

Rebuilds and thickens the uterus lining

Causes secondary sexual characteristics
Stimulates sperm production

Causes secondary sexual characteristics

Menstrual cycle

The menstrual cycle begins at puberty in females. Each cycle lasts about 28 days, and during each cycle one egg is released. The menstrual cycle stops when menopause begins.

Day 1–5 of the menstrual cycle is menstruation. During this time the uterus lining is broken down and discharged from the body. This is known as a period.

Day 5–14 the uterus lining is rebuilt and thickens. Around day 14 ovulation occurs.

Day 14–28 the uterus lining is maintained. If the egg is not fertilised by day 28, hormone levels fall, the uterus lining breaks down and the cycle restarts.

If the egg is fertilised, the uterus lining is maintained throughout pregnancy.

Menstrual cycle showing the uterus lining breaking down and rebuilding over 28 days

Role of the hormones in the menstrual cycle.

Below is a summary table for the four main hormones involved in the menstrual cycle.

HormoneWhere it is producedRole in menstrual cycle
FSH (Follicle stimulating hormone)Pituitary glandCauses an egg to mature in the ovary and stimulates oestrogen production
OestrogenOvaryRebuilds and thickens the uterus lining, inhibits release of FSH, stimulates LH release
LH (Luteinising Hormone)Pituitary glandTriggers ovulation (release of egg from ovary)
ProgesteroneOvary(after ovulation)Maintains uterus lining, inhibits FSH and LH, drop in levels of progesterone causes menstruation

Day 1–5:
FSH is released and causes an egg to mature in the ovary.

Day 6–13:
The ovary secretes oestrogen, which rebuilds the uterus lining.
As oestrogen levels rise, FSH release is inhibited and LH release is stimulated.

Day 14:
LH levels peak, causing ovulation. The egg is released from the ovary.

Day 15–28:
The ovary secretes progesterone, which maintains the uterus lining and inhibits FSH and LH release.
If the egg is not fertilised, progesterone levels fall and the cycle restarts.

See the graph below

Menstrual cycle with the 4 hormones

Practice Questions

1.Which hormone causes an egg to mature in the ovary?

2.Describe the role of oestrogen in the menstrual cycle.

3.Explain why high progesterone levels prevent pregnancy from occurring again immediately.