AQA GCSE Homeostasis (Biology)

Homeostasis

Homeostasis is the regulation of the internal conditions of a cell or organism to maintain optimum conditions for function in response to internal and external changes.

Homeostasis maintains optimum conditions for enzyme action and all cell functions.

Optimum conditions for enzyme action

Enzymes work best under certain conditions, their activity is affected by temperature and pH. 

Each enzyme has an optimum temperature where it has the maximum rate of reaction. 

If the temperature is too low, then the rate of reaction will be too slow to sustain life. 

If the temperature is too high, then the enzyme is denatured and the reaction will stop, so life cannot be sustained. 

Cell functions

Cell functions are the processes that happen inside cells that keep an organism alive. These processes are mostly controlled by enzymes, which is why homeostasis is important.

Examples of cell functions

Cell FunctionWhat happens in the cellLink to homeostasis
RespirationGlucose is broken down in cells to release energyNeeds the correct temperature, glucose concentration and water levels for enzymes to work efficiently
Enzyme controlled reactionEnzymes speed up chemical reactions in cellsEnzymes only work at optimum temperature and pH. Extreme conditions will slow down reactions or denature enzymes
Cell growth and divisionCells grow and divide to make new cellsRequires enzymes and energy from respiration, which depend on stable internal conditions.
Transport of substancesSubstances move in and out of cells by diffusion, osmosis and active transportWater balance affects osmosis

Examples of controlled conditions.

In the human body, conditions that are controlled include:

Blood glucose concentration

Core body temperature

Water levels

There are other examples of conditions that homeostasis will control.

Blood Glucose Concentration

Homestasis ensures that there is a steady supply of glucose for respiration and prevents the glucose levels being too high or too low. 

Pancreas will monitor blood glucose concencentration. If the blood glucose concentration needs to be adjusted the pancreas will secrete either insulin or glucagon into the blood.

Core Body Temperature

Core body temperature is maintained at approximately 37°C.

This temperature is important for enzyme activity, see the notes earlier in the page for more detail.

The skin, blood vessels, sweat glands and thermoregulatory centre in the brain work together to help control core body temperature.

Water Levels.

Water levels need to be controlled to prevent cells losing or gaining too much water by osmosis. 

Water levels are controlled by the kidneys in the body and a hormone called ADH. 

Control Systems

Homeostasis involves automatic control systems. There are two types:

1.Nervous responses

2. Chemical (Hormonal) responses

Nervous responsesChemical (Hormonal) responses
FasterSlower
Short lastingLonger lasting
Use electrical impulsesInvolve hormones in blood
Example: body temperature controlExample: blood glucose control

Control System

All control systems include:

Model of a control system for homeostasis

Receptors

Receptors are cells that detect stimuli. 

Stimuli are changes in the external or internal environment such as change in light intensity, or change in temperature.

Examples of receptors include:

Temperature receptors in the skin, or glucose receptors in the pancreas.

Coordination centres

A coordination centre will receive and process information. 

Once they have coordinated a response, a signal will be sent to an effector.

Examples of coordination centres include brain, spinal cord and pancreas.

The pancreas is a coordination centre because it detects changes in blood glucose and releases hormones that tell effectors how to respond.

Brain and spinal cord tend to use neurones, but pancreas using hormones.

Effectors

An effector will bring about a response, they are typically muscles or glands

In bringing about a response, they will restore optimum conditions. 

When a muscle is stimulated it will contract to cause movement e.g. shivering.

When a gland is stimulated it will secrete hormones e.g. pancreas secreting the hormone insulin.

Practice Questions

1.Define the term homeostasis

2. Outline the importance of maintaining core body temperature

3. Name the three main parts to a control system.